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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of Behcet's disease (BD)
ncRNA name IL-6 siRNA
ncRNA Category siRNA
Disease name Behcet's disease (BD)
Species Mus musculus
Tissues/Cell_line macrophages
Methods siRNA transfection, RT-PCR, qPCR
Expression pattern associated
Functional description Downregulation of IL-6 improved the inflammatory symptoms in BD mice through upregulation of regulatory T cells and inhibition of Th17 cells.
PubMed ID 19092856
Year 2009
Title Interleukin-6 small interfering RNA improved the herpes simplex virus-induced systemic inflammation in vivo Behcet's disease-like mouse model.
Drug-related ncRNA NO

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